The relationship between exercise training and nitric oxide-related parameters was examined in a cross-sectional study and an intervention study. A crosssectional study using 184 employees was conducted to observe the association of exercise habits with serum arginase (ELISA and activity), L-arginine, L-citrulline, L-ornithine, NOx, exhaled nitric oxide, blood pressure, FEV1%, hs-CRP, HDL- cholesterol, IgE, and life style factors. An intervention study was also conducted to evaluate the changes of serum arginase I, nitric oxide-related parameters, and mRNA levels of antioxidant enzymes in blood monocytes before and after 1 h of aerobic exercise training per day for a month.
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