by admin | Sep 9, 2022 | Appendix II, Cardiac/Vascular Support
N itric oxide (NO) is a recently appreciated regulator molecule for leukocytes, endothelial cells of blood vessels, and neurons in the brain and peripheral nervous system. NO is handled in the body quite differently from other autacoids and neurotransmitters such as...
by admin | Sep 9, 2022 | Appendix II, Cardiac/Vascular Support
Dysfunction of the normally protective endothelium is found in several cardiovascular diseases, including atherosclerosis, hypertension, heart failure, coronary heart disease, arterial thrombotic disorders, and stroke. Endothelial dysfunction leads to nitric oxide...
by admin | Sep 9, 2022 | Appendix II, Cardiac/Vascular Support
Nitric oxide (NO) is a ubiquitous, naturally occurring molecule found in a variety of cell types and organ systems. In the cardiovascular system, NO is an important determinant of basal vascular tone, prevents platelet activation, limits leukocyte adhesion to the...
by admin | Sep 9, 2022 | Appendix II, Cardiac/Vascular Support
TAside from its importance for blood flow and blood pressure via endothelium-dependent vasodilation, endothelial NO synthase (eNOS) has been shown to have numerous other vascular protective effects including, but not limited to, inhibition of platelet aggregation and...
by admin | Sep 9, 2022 | Appendix II, Cardiac/Vascular Support
Nitric oxide (NO) is an important mediator in both health and disease. In addition to its effects on vascular tone and platelet function, it plays roles in inflammation and pain perception that may be of relevance in osteoarthritis. Many patients with osteoarthritis...
by admin | Sep 9, 2022 | Appendix II, Cardiac/Vascular Support
Inducible nitric oxide synthase (iNOS) activity increases in acute and chronic inflammatory lung diseases. Imaging iNOS expression may be useful as an inflammation biomarker for monitoring lung disease activity. We developed a novel tracer for PET that binds to iNOS...
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