Producing Nitric Oxide
A Signaling Molecule
In your body, nitric oxide is a signaling molecule involved in several physiological and pathological processes. Cell signaling/communication is the ability of a cell to receive, process, and transmit signals with its environment and with itself.
[3] It is a fundamental property of all cells in every living organism.[4] Signals that originate from outside a cell can be physical agents like electrical voltage, temperature, light, or chemical signals. Cell signaling can occur over short or long distances. Each cell is programmed to respond to specific extracellular signal molecules, and is the basis of development, tissue repair, immunity, and homeostasis.[5]
Your body needs to make nitric oxide out of component parts, which include vitamin C and nitrates. Without enough of these component parts, you will not be able to produce enough nitric oxide. This impacts a number of body systems, including the immune system, circulatory system, exercise and muscle performance.[6] Errors in signaling interactions may cause problems in healthy body functions, such as cancer, autoimmunity, and diabetes. [7] [8] [9] [10]
PDF Downloads:
Wavelength- and irradiance-dependent changes in intracellular nitric oxide level
Blue Laser Light Increases Perfusion of a Skin Flap Via Release of Nitric Oxide
from Hemoglobin
Enhancement of nitric oxide release from nitrosyl hemoglobin and nitrosylmyoglobin by red/near infrared radiation: Potential role in cardioprotection
Light-induced-nitric-oxide-release-in-the-skin-beyond-UVA-and-bl_2021_Nitric.
pdf
How Can I Encourage My Body to Produce Nitric Oxide?
For optimal nitric oxide production, increase your intake of nitrate-rich vegetables and exercise at least 30 minutes per day. But what if you don’t want to change your diet, or have difficulty finding the time, energy or ability to increase exercise?
Research shows the results with various electrical voltage, light, and temperature introduction. These articles detail studies on body vibration, infrared light, and increased temperature:
References:
[1] Britannica, The Editors of Encyclopaedia.
“nitric oxide”. Encyclopedia Britannica, 25 Aug. 2017, https://www.britannica.com/science/nitric-oxide. Accessed 9 January 2022.
[2] Britannica, The Editors of Encyclopaedia.
“nitric oxide”. Encyclopedia Britannica, 25 Aug. 2017, https://www.britannica.com/science/nitric-oxide. Accessed 9 January 2022.
[3] Neitzel, James; Rasband, Matthew. “Cell communication”. Nature Education. Retrieved 29 May 2021.
[4] Lodish, Harvey; Berk, Arnold.; Kaiser, Chris A.; Krieger, Monty; Scott, Matthew P.; Bretscher, Anthony; Ploegh, Hidde; Matsudaira, Paul (2008). “Cell signaling I: Signal transduction and short-term cellular processes”. Molecular Cell Biology (6th ed.). New York: W.H. Freeman and Company. pp. 623–664.
ISBN 978-0716776017.
[5] Kumar P, Mina U (2014). Life science
fundamental and practice part I. New Delhi,
India: Pathfinder Publication.
[6] WebMD Medical Reference. Healthy
Foods to Boost Nitric Oxide. https://www.webmd.com/diet/healthy-foods-nitric-ox-
ide#1.
[7] Vlahopoulos SA, Cen O, Hengen N,
Agan J, Moschovi M, Critselis E, Adamaki M,
Bacopoulou F, Copland JA, Boldogh I, Karin
M, Chrousos GP (August 2015). “Dynamic
aberrant NF-kB spurs tumorigenesis: a new
model encompassing the microenvironment”.
Cytokine & Growth Factor Reviews. 26 (4):
389–403. doi:10.1016/j.cytogfr.2015.06.001.
PMC 4526340. PMID 26119834.
[8] Wang K, Grivennikov SI, Karin M (April
2013). “Implications of anti-cytokine therapy in colorectal cancer and autoimmune diseases”. Annals of the Rheumatic Diseases. 72 Suppl 2: ii100–3. doi:10.1136/annrheum-
dis-2012-202201. PMID 23253923. S2CID 40502093. We have shown interleukin (IL)-6 to be an important tumour promoter in early colitis-associated cancer (CAC).
[9] Solinas G, Vilcu C, Neels JG, Bandyopadhyay GK, Luo JL, Naugler W, Grivennikov S, Wynshaw-Boris A, Scadeng M, Olefsky JM, Karin M (November 2007). “JNK1 in hematopoietically derived cells contributes to diet-induced inflammation and insulin resistance without affecting obesity”. Cell Metabolism. 6 (5): 386–97. doi:10.1016/j.cmet.2007.09.011. PMID 17983584. Activation of JNKs (mainly JNK1) in insulin target cells results in phosphorylation of insulin receptor substrates (IRSs) at serine and threonine residues that inhibit insulin signaling.
[10] Smith RJ, Koobatian MT, Shahini A, Swartz DD, Andreadis ST (May 2015). “Capture of endothelial cells under flow using immobilized vascular endothelial growth factor”. Biomaterials. 51: 303–312.
doi:10.1016/j.biomaterials.2015.02.025. PMC 4361797. PMID 25771020.
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